Coagulase - negative staphylococcal skin carriage among NICU personnel : from 1 population to infection
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Coagulase-negative staphylococcal skin carriage among neonatal intensive care unit personnel: from population to infection.
Coagulase-negative staphylococci (CoNS) are a major cause of sepsis in neonatal intensive care units (NICU) worldwide. Infecting strains of these commensal bacteria may originate from NICU personnel. Therefore, we studied the characteristics of CoNS isolates from NICU personnel and compared them to those of isolates from the general population and from sepsis patients. Furthermore, we studied t...
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Coagulase-negative staphylococci (CoNS) are a leading cause of sepsis in the neonatal intensive care unit (NICU) setting. To evaluate the hypothesis that isolates of CoNS associated with disease belong to hypervirulent clones, as opposed to being drawn randomly from the neonatal unit carriage flora, we conducted a prospective, case-controlled study in a busy NICU. Using pulsed-field gel electro...
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18 Background 19 Nasal colonization with coagulase-negative Staphylococcus (CoNS) has been 20 described as a risk factor for subsequent systemic infection. In this study, we aimed to 21 evaluate the profile of CoNS isolates colonizing the nares of children admitted to a 22 neonatal intensive care unit (NICU) of a major city located in central Brazil. 23 Methods 24 We assessed CoNS carriage at a...
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The influence of hexachlorophane disinfection on the bacterial hand flora of hospital personnel has been examined. Hexachlorophane effectively reduced the total number of bacteria and the staphylococcal carriage. Gram-negative bacilli were isolated from 18.8% of the personnel, and 13% of the carriers continued to carry Gram-negative bacilli for more than six months. The carrier rate was signifi...
متن کاملThe ica operon and biofilm production in coagulase-negative Staphylococci associated with carriage and disease in a neonatal intensive care unit.
Coagulase-negative staphylococci (CoNS) are a major cause of sepsis in the neonatal intensive care unit (NICU). We evaluated the hypothesis that the ica operon and biofilm production are associated with CoNS disease in this setting. CoNS associated with bacteremia or blood culture contamination and from the skin of infants with CoNS bacteremia or healthy controls were obtained during a prospect...
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